May 21, 2009 (CIDRAP News) – In a search for factors that may give some patients a protective edge against novel H1N1 influenza, researchers said today that adults, especially those older than 60, appear to have some cross-antibody response but that seasonal influenza vaccines appear unlikely to offer any protection.The findings, from scientists at the US Centers for Disease Control and Prevention (CDC) appear in tomorrow’s edition of Morbidity and Mortality Weekly Report (MMWR). Results are based on microneutralization and hemagglutination inhibition assays on child and adult serum specimens that were used in previous vaccine studies by the CDC as well as its academic and industry partners.Epidemiologic patterns in the novel flu outbreak have consistently shown the disease taking its hardest toll on younger people—in the United States, 64% of the novel flu cases have occurred in the 5- to 24-year-old age-group. Officials have wondered if older people haven’t yet been exposed to the strain in the community or if another factor, such as preexisting immunity, is providing some protection against the virus. Only 1% of cases have occurred in people over age 65.Researchers assessed cross-reactive antibody levels to the novel influenza H1N1 virus in cohorts of children and adults before and after they had been vaccinated with a seasonal flu vaccine during any of the past four seasons.Before vaccination, children showed no cross-reactive antibody reaction to the new flu strain. However, the antibody was detected in 6% to 9% of adults ages 18 to 64 and in 33% of those older than age 60.Vaccination with any form of the seasonal flu vaccine did not provoke a response to the novel strain in children. Adults ages 18 to 64 who had been vaccinated showed a slight response to the new strain: a twofold increase compared with 12-fold to 19-fold increases seen against the seasonal H1N1 strain. No increase in cross-reactive antibody response was seen in people over age 60 who had been vaccinated.”These data suggest that receipt of recent (2005-2009) seasonal influenza vaccines is unlikely to elicit a protective antibody response to the novel influenza A (H1N1) virus,” the CDC reported.Though the number of sera samples from children was small, the findings suggest that US children are serologically naive to the new virus, the researchers concluded. However, the analysis suggests adults—especially those older than 60—have some degree of preexisting immunity to the novel strain.Anne Schuchat, MD, interim deputy director for the CDC’s science and public health program, today at a media briefing urged caution in interpreting the results. Cross-reactive antibody assessment is an indirect measure of immune response, and though the findings are interesting, they’re not definitive, she said. “The laboratory findings we’re reporting seem to correlate with the epidemiologic data that we have so far.”Another reason to not over-interpret the results, she said, is that the microneutralization assay was used as a surrogate and isn’t the standard test the CDC uses against influenza viruses. (Microneutralization assays appear more sensitive, but researchers have not agreed on clinical correlates for the method.) She also said the study findings are based on relatively small numbers of patient serum samples.The response in older people could be explained by exposure to a related virus, exposure to a seasonal flu vaccine that provided protection, or that immune response to the new virus might be similar to that of other viruses, Schuchat said. However, she added that CDC virologists have compared the novel strain with past viruses and found that the new one is very different. “It’s not a close genetic match,” she said.She also said experts aren’t very impressed by the prevaccination-to-postvaccination ratio of 2:1 that suggests a weak response to the new virus. “That’s pretty wimpy,” Schuchat said, adding that the ratio for seasonal flu vaccines ranges around 12:1. “Wouldn’t it be great if there was boosting? But we don’t think we have sufficient evidence of that at this point,” she said.CDC. Serum cross-reactive antibody response to a novel influenza A (H1N1) virus after vaccination with seasonal influenza vaccine. MMWR 2009 May 22;58(19):521-4 [Full text]See also:May 6 CIDRAP News story “Fewer senior swine flu cases may hint at protection”
“It’s a joy for me and for everyone that he’s back,” Scaloni told a news conference on Thursday.“Now what remains is try and get the team to play along with him and get the best out of him. We’re all very happy that he’s back.”“It is the others who have to take that step so that Argentina can return to the level it had,” added Scaloni, who replaced Jorge Sampaoli as coach following the last-16 defeat by France at the 2018 World Cup.Messi has missed six friendlies since the tournament in Russia but many believe he will be an essential part of the team that travels to Brazil for the Copa America, which kicks off June 14.“We have a way of playing and feeling football in these six games we’ve had. We’re not going to change it, that (Messi) is coming is more incentive for us and another addition.”“We’ve played different systems and we’re going to do it in the same way, added to his great quality,” Scaloni added.“But we need the rest, who are all top players and key figures at their clubs, to give us that bit extra to try and be a great team.”Scaloni refused to be drawn on whether Messi would also travel with the squad for next week’s friendly against Morocco in Tangier, but said he would not risk the Barcelona forward’s fitness.The news that Messi would be involved for the game at Atletico Madrid’s Wanda Metropolitano ground pleased Venezuela coach Rafael Dudamel.“The presence of the best player in the world lifts the game’s expectation,” Dudamel said.“For us to take on Argentina is a good way to see how we stack up. The return of Lionel Messi makes the demands on us extremely high.”0Shares0000(Visited 1 times, 1 visits today) 0Shares0000Lionel Messi hasn’t played for Argentina since last year’s World Cup © AFP / BENJAMIN CREMELMADRID, Spain, Mar 22 – Lionel Messi will start Friday’s friendly against Venezuela in Madrid as he makes his return for Argentina following a self-imposed eight-month exile, coach Lionel Scaloni confirmed.Scaloni said that Messi would line up alongside Inter Milan forward Lautaro Martinez and Atlanta United’s Gonzalo Martinez in attack as he revealed his full starting team.
If you’re going to score goals in FIFA 19, you’re going to need a superstar playmaker in your side to pull the strings.Every top team has one, but who are the best in the world according to EA Sports? MONEY RANKED Forbes list reveals how much Mayweather, Ronaldo and Messi earned this decade 20= Santi Cazorla (Villarreal) – Passing = 85 (Overall rating = 79)20= Emre Belozoglu (Istanbul Basaksehir) – Passing = 85 (Overall rating = 80)19. Eden Hazard (Chelsea) – Passing = 86 (Overall rating = 91) Premier League Team of the Season so far, including Liverpool and Leicester stars Well, with their extensive rating system, they’ve given their view in the new game which is set to be released.We’ve already found out who they have rated as the best player overall, and the fastest too.But who do they believe are the current passmasters of the beautiful game? Find out below. 8. Dani Parejo (Valencia) – Passing = 88 (Overall rating = 86)7. James Rodriguez (Bayern Munich) – Passing = 88 (Overall rating = 88)6. Koke (Atletico Madrid) – Passing = 88 (Overall rating = 85)5. Cesc Fabregas (Chelsea) – Passing = 88 (Overall rating = 84)4. Christian Eriksen (Tottenham Hotspur) – Passing = 89 (Overall rating = 88)3. Toni Kroos (Real Madrid) – Passing = 89 (Overall rating = 90)2. Luka Modric (Real Madrid) – Passing = 90 (Overall rating = 91)1. Kevin De Bruyne (Manchester City) – Passing = 92 (Overall rating = 91) Top nine Premier League free transfers of the decade 6 This quartet are all amongst the best passers in FIFA 19. BEST OF 6 ADVICE 6 6 no dice 14. Paul Pogba (Manchester United) – Passing = 86 (Overall rating = 88)13. Hakim Ziyech (Ajax) – Passing = 86 (Overall rating = 82)12. Andres Iniesta (Vissel Kobe) – Passing = 87 (Overall rating = 87)11. David Silva (Manchester City) – Passing = 87 (Overall rating = 89) Ronaldo warned Lukaku how hard scoring goals in Serie A would be before Inter move 18. Ever Banega (Sevilla) – Passing = 86 (Overall rating = 83)17. Mesut Ozil (Arsenal) – Passing = 86 (Overall rating = 86)16. Miralem Pjanic (Juventus) – Passing = 86 (Overall rating = 86)15. Philippe Coutinho (Barcelona) – Passing = 86 (Overall rating = 88) 10. Ivan Rakitic (Barcelona) – Passing = 87 (Overall rating = 87)9. Lionel Messi (Barcelona) – Passing = 88 (Overall rating = 94) REPLY huge blow Oxlade-Chamberlain suffers another setback as Klopp confirms serious injury Which teams do the best on Boxing Day in the Premier League era? Latest Football News Berahino hits back at b******t Johnson criticism – ‘I was in a dark place at Stoke’ Every time Ally McCoist lost it on air in 2019, including funny XI reactions 6 Son ban confirmed as Tottenham fail with appeal to overturn red card Where Ancelotti ranks with every Premier League boss for trophies won shining REVEALED 6 REVEALED
Drake University golfer Haeri Lee was named MVC Women’s Golfer of the Week Wednesday after earning medalist honors in Drake’s win at the UNI Women’s Invitational. The freshman battled difficult conditions to post consecutive rounds of 75 to finish at the top of the 32 golfer field.Lee finished with a 36-hole score of 150 (75-75) to outpace fellow freshman Kristen Giles by three strokes. The first-place finish is Lee’s sixth consecutive top-20 finish, and her third top-10 finish this season. Lee is averaging 76.3 strokes per round, which is a team-best for the Bulldogs.The Bulldogs will travel to Raymore, Mo. for the Kansas City Intercollegiate hosted by UMKC, April 8-9. Print Friendly Version